Opponent’s options: GREX 4l, WRY b8
Scoring options: FURY b7, EYEFUL k2, FEY m2
Setup potential: Yes

You’re simply too far behind to allow GREX, so your best play necessarily has to block that. While it’s easy to tunnel vision looking for setups looking at o1, the best play is actually a setup below that, playing UEY m2 to set up FEM.