Opponent’s options: Row 3 plays, 20 point plays to floaters
Scoring options: ACKNOW o7, CAWK/AWK row 6
Setup potential: No

Since you have two spots for your ACK tiles and the higher scoring spot is difficult to block, you should instead focus on playing off your remaining tiles. While DIENE leaves your opponent decent options, AINEE j1 (7) blocks most of your opponent’s good scoring options while still preserving both ACK spots.